Medrol, a corticosteroid drug, is used to reduce inflammation and improve symptoms in a variety of disorders, including rheumatoid arthritis, acute gouty arthritis, and severe cases of asthma. Medrol may be given to people to treat primary or secondary adrenal cortex insufficiency (inability of the adrenal gland to produce sufficient hormone). It is also given to help treat the following disorders:

Severe allergic conditions (including drug-induced allergic states)
Blood disorders (leukemia and various anemias)
Certain cancers (along with other drugs)
Skin diseases (including severe psoriasis)
Connective tissue diseases such as systemic lupus erythematosus
Digestive tract diseases such as ulcerative colitis
High serum levels of calcium associated with cancer
Fluid retention due to nephrotic syndrome (a condition in which damage to the kidney causes loss of protein in urine)
Various eye diseases
Lung diseases such as tuberculosis
Worsening of multiple sclerosis